Karpenisi is an especially favourite destination in all seasons attracting many visitors mainly for the ski centre and the innumerable beauties of the area. Access to Karpenisi is not difficult, it however requires attention especially in the winter months due to the altitude and problems with the road conditions from the weather. The usual gateway to Karpenisi and all of Evrytania is from the east via Tymfristo and its from here most visitors from Athens and Thessaloniki arrive.
The distance from Athens to Karpenisi via Lamia is 286km and takes about 3 hours.
Thessaloniki to Karpenisi is of course further, the distance being 372km and takes about 3 hours 50 minutes.
The distance from Larissa to Karpenisi via Lamia is 225km and takes 2 hours 40 minutes.
Patras is 198km from Karpenisi and the journey lasts about 2 hours 40 minutes.